Publication Alert: A Global Field Study of the International Classification of Diseases (ICD-11) Mood Disorders Clinical Descriptions and Diagnostic Guidelines

In a study led by Dr. Cary Kogan, faculty members of the Columbia Global Global Mental Health Programs, including Drs. Tahilia Rebello, Francine Cournos, Michael First, Kathleen Pike, and Geoffrey Reed, collaborated with international colleagues to conduct a global study evaluating the accuracy and clinical utility of the ICD-11 Clinical Descriptions and Diagnostic Guidelines for mood disorders compared to the ICD-10 guidelines.

More about the study: 1357 clinician members of the World Health Organization’s Global Clinical Practice Network, who completed the study in English, Spanish, Japanese or Russian, were randomly assigned to apply ICD-11 or ICD-10 guidelines to diagnose patients presented in case vignettes. Overall, it was found that accuracy and clinical utility were the similar for both classifications, with ICD-11 demonstrating some potential advantages. However, clinicians using the ICD-11 had difficulty differentiating bipolar type I disorder from bipolar type II and also had difficulty applying revised severity levels to depression. Informed by these results, the ICD-11 guidelines were updated to further clarify these identified areas and training programs will be developed to enhance clinicians’ ability to accurately diagnose mood disorders.

Citation: Kogan, C. S., Maj, M., Rebello, T., Keeley, J. W., Kulygina, M., Matsumoto, C., Robles, R., Huang, J., Zhong, N., Chakrabarti, S., Figueira, M. L., Stein, D., Strakowski, S. M., Garcia-Pacheco, J. A., Burns, S., Montoya, M., Andrade, L., Ayuso-Mateos, J. L., Arango, I., Balhara, Y. P. S., Bryant, R., Cournos, F., Porto, J. A. D., Meyer, T. D., Medina-Mora, M.-E., Gureje, O., First, M. B., Gaebel, W., Khoury, B., Krasnov, V. N., de Jesus Mari, J., Maruta, T., Pike, K. M., Roberts, M. C., Sharan, P., Zhao, M., & Reed, G. M. (2021). A global field study of the International Classification of Diseases (ICD-11) mood disorders clinical descriptions and diagnostic guidelines. Journal of Affective Disorders, 295(1), 1138-1150. Doi:

This full article is available here.